163400+ entries in 0.107s
a111: Logged on 2017-08-28 20:43 asciilifeform: kanzure: mike w promised myostatin inhibitor
to me in 2007 !!1111 where is it ?!
mircea_popescu: sane person would have stopped
there. "this risk can not be avoided ; abandon du
travail"
mircea_popescu: lol "while
this risk can not be avoided entirely... here's how im not giving up".
kanzure: bad abstract parse
there. it ends half-way
through.
mircea_popescu: kanzure i lean on people all
the damned
time, what are you
talking about.
a111: Logged on 2017-08-09 00:40 asciilifeform: No one else did. Not
theymos, not knighmb, not pirate, not silbert, not Jihan Wu. Not satoshi or asciilifeform.
kanzure: so just hoard a bunch of power and don't provide much signal regarding its application or likely application. is
this some sort of gmaxwell-level fear of "unintentionally causing others
to agree with you, by unethically signaling
to
them an idea
that
they shouldn't have had in
the first place" bullshit?
mircea_popescu: actually part of republican doctrine,
there's no standard policies in all sorts of shocking places.
kanzure: alright so
the argument is
that
to whatever extent
there's a modellable aspect,
that's a failure mode and not necessarily a preference
a111: Logged on 2017-07-18 18:23 mircea_popescu: asciilifeform understand
this bit of GT :
the knowledge of all
the
things you don't know
thereby constructs a sybil of you.
mircea_popescu: funny you should mention
that,
there's also a discussion re rng and power in
teh logs.
kanzure: you could safely argue it would look like a plot of
the sha256 function against a graph, but i would also be surprised
to hear
that
☟︎ kanzure: i'd settle for "observed
tendencies or use of power
that would probably fail without such power"
mircea_popescu: and
the bad notation makes you go into walls, as per "since it's power it must have goal"
kanzure: it's just how i work, i internalize
things
kanzure: i am
trying
to ascertain what you exercise power for
mircea_popescu: there's some work in
the log re creating mechanical-mp, but mostly at
the lulz stage.
mircea_popescu: because
the political power is a super-2 exponential on smarts, whereas cost is a logarithmic on stupidity, it's very easy
to be powerful hanging out with smart people. almost as easy as it is
to go bankrupt hanging out with many people.
☟︎ mircea_popescu: anyway, in practical
terms i am politically powerful because i've successfully protected a bunch of smart people from idiocy for years, and
they have
the (pewrhaps unwarranted) expectation
this may continue.
mircea_popescu: you're more
than welcome
to go again, but you'll need a decent definition of effort and some sort of proof it's directable.
a111: Logged on 2017-04-07 20:17 mircea_popescu:
http://btcbase.org/log/2017-04-07#1639964 << one of
the (~the~ ?) advantage of
tmsr work for intelligent folk is
that
there isn't a braindamaged/choiceless manager in
the loop going "i know it's stupid but it must be done".
mircea_popescu: i was not arguing at you. we were examining your model
together, and it came out unconvincing, and
then we were left
trying
to make something of
the pieces.
kanzure: you were arguing
to me
that directed effort is irrelevant (or something) so i'm
trying
to ascertain what your proposed alternative is
mircea_popescu: also funny, if not funnier : apparently nature very much favours
the republican outlook. "divide
teh people into
two groups. blender one for
the choline, vx
the other."
kanzure: that's sort of rude isn't it. wouldn't it be less
total noise
to just answer instead of either one of us wasting our
time?
mircea_popescu: kanzure
the
trying
to figure it out, no.
the expecting i'll justify myself, yes.
kanzure: if
this knowledge only enables you
to feel alright about whatever cause passes your fancy for
the moment
then i would argue you're engaging in a lot of effort for a rather
trivial outcome.
kanzure: is "trying
to figure out whether mircea_popescu is just babbling on a blog" also a "political act"?
mircea_popescu: asciilifeform im strictly going by
the above "woman will do anything you wanrt provided it is what she ewas goping
to do anyway". afaik, spiders do actually make variants of it.
☟︎ kanzure: "".. isn’t
the only one working
to clone a mammoth.
There’s also Hwang Woo-suk’s Korean dog-cloning lab, Soaam
Technologies [....] He was
the one who claimed
to clone human cells, but it
turns out he had been forcing his students
to donate
their eggs, and secondly
that his clone cells are fraudulent, so he’s
trying
to resurrect his reputation by being
the first
to clone ...
mircea_popescu: (speaking of which... if what you want is in
the vein of yl-cholinesterase, maybe
try engineering spiders ?
BingoBoingo: <mircea_popescu> it's in
the last link, re
teh HeLa. << For further reading ask Hussein Bahamas about
the
trechery of Big Headed Yakub.
phf: ah makes sense, for some reason i
thought 3d printers went in
the direction of spiroligomers, but hackerspace for which i was mocked is running a CRISPR project in
their fridge so
this is consistent
kanzure: no i just fed it
to my bioreactor person
to see what he would design for me. butyrylcholinesterase proposal will be forthcoming.
mircea_popescu: you can get bacteria
to do anything you want
them
to ; provided you want
them
to do something
they were going
to do already. gotta be a metabolic leftover.
a111: Logged on 2017-08-28 20:30 asciilifeform: kanzure: objective was
to economically make (by
the kg) a (modified) butyrylcholinesterase
kanzure: "normally
the left derives semantic authority from
threats of mob violence/witch hunts; what does mircea_popescu have?"
kanzure: you insert
the reagents at
the start of
the reaction,
the polymerase is not a permanent component of
the machine.
mircea_popescu: asciilifeform no i know.
the problem with dna amplification with it is
that (on
tech i recalled)
the required enzyme gets periodically destroyed.
mircea_popescu: ahahahaha wait,
they switched
to
termophillic bacteria polymerase ?! god help us.
kanzure: asciilifeform: i rescued a silly open-source nanotech cad program from being deleted and forgotten. however, i did not fund its original development. is
this
the
thing you're
tlaing about?
https://github.com/kanzure/nanoengineer kanzure: anyway,
the reason for "infeasibility" claims is because people
try
to do impossible
things;
there have not been infeasibility claims regarding genome synthesis or assembly.
kanzure: that pic was actually
taken from a volunteer birdhouse assembly workshop
mircea_popescu: shit i wish we
thought of
this in
the early days of "fpga mining".
kanzure: and
then lasercut plywood because we're all hipsters and our eyes don't bleed
mircea_popescu: phf
the more amusing
thing here is
that only last week i was wondering where
the 3d printing folk went.
kanzure: (openpcr actually isn't
that cheap. it's sort of annoying.)
kanzure: yes and
then people made cheapo
thermocyclers. what's wrong with
that?
mircea_popescu: so far it's not altogether clear what specirfically you're arguing for
tbh.
kanzure: well i'm not one
to argue for inflated resources, sure
mircea_popescu: kanzure " Obviously
there is no possiblity of meaning outside of a structure of authority, and
the authority can not be predicated on
the meaning."
☟︎☟︎☟︎☟︎☟︎☟︎☟︎☟︎☟︎☟︎ kanzure: asciilifeform: insufficient money i
think. although
this might be a bad reason. i could accept
that. nobody calls me on
this
type of
thing.
kanzure: authorities definitionally can't babble? show me how
that works.
a111: Logged on 2017-08-28 23:03 kanzure: "productive results" in my book include cheap genome synthesis,
the results of which are easily in reach (engineers haven't even bothered
to optimize inkjet firing rate. "boo hoo it overheats and we haven't
tried cooling").
mircea_popescu: take a more productive
tack, like say something concrete.