log☇︎
1100+ entries in 0.057s
kanzure: fuckers
kanzure: wait my math is fine
kanzure: oh my god i am bad at math
kanzure: about to get unvoiced i think. could someone offer mircea_popescu a link to the right place in the logs for the eugenics war.
kanzure: first you have to kill everyone who has ever had a headache...
kanzure: i don't know any hereditary magic tricks to eliminate headaches but that should be doable.
kanzure: just some guy it doesn't matter
kanzure: jihan has been quite friendly so far ☟︎
kanzure: well i was thinking about just going for the heart of the whole thing (designer genomes/eugenics) and go after those bathtubs
kanzure: i read all logs everywhere. it's sort of my thing.
kanzure: pore secretion?
kanzure: thanks for playing
kanzure: ecoli is an actual biology
kanzure: well there's some ecoli results for you.
kanzure: http://diyhpl.us/wiki/transcripts/hgp-write/2016-05-10/recoding-ecoli-to-57-codons/
kanzure: http://diyhpl.us/wiki/transcripts/hgp-write/2016-05-10/synthesizing-a-prototrophic-human-genome/
kanzure: http://diyhpl.us/wiki/transcripts/hgp-write/2016-05-10/ultra-safe-cell-line/
kanzure: where's your "causual link" now
kanzure: also, i am part of hgp-write (basically human genome project 2.0) one of our projects is removing 7 codons from the genome to render human biology impervious to all existing viruses. ☟︎
kanzure: wwc1 t/t carriers tend have >19% improvement in working memory performance
kanzure: optogenetics is one way of interactive toggle (usuaully using neuronal receptors but there are other techniques such as light-sensitive cas9/recombinases/etc)
kanzure: anyway, you don't need to focus merely on small mutations, you can also voluntarily delete chunks of chromosomes or whatever ☟︎
kanzure: yes well online interactive toggling is also a possible thing
kanzure: yes a lot of biology is stupid i'm not sure what your concern is
kanzure: and also the effect size is minimal in many cases.
kanzure: well in many cases the mutations listed on that page have not been documented (on that page) as impacting positively or negatively. so the document should not be considered a definitive lookup table. ☟︎
kanzure: so i guess to answer your question, ethnic cleansings?
kanzure: here's some background on plausible modifications that are aleady well known http://diyhpl.us/wiki/genetic-modifications/
kanzure: i am proposing an aggressive timeline like 100 designer baby genomes by 2030 and then 1 million designer babies by 2045
kanzure: basically i sat down and tried to figure out what is the most controversial idea i could possibly construct ☟︎
kanzure: should i be hurt that he doesn't know me?
kanzure: yeah maybe not appropriate for public logs at the moment
kanzure: i have begun to master the art of sleeptyping so sleep is no longer an inconvenience
kanzure: alright well that's lame. ☟︎
kanzure: where precisely do i go to pitch mircea on eugenics 2.0?
kanzure: greetings
kanzure: sup
kanzure: well why bother with breathing at that point? what?
kanzure: way ahead of you
kanzure: of course
kanzure: asciilifeform: also.. we should run a (human) selective breeding program for cryoresuscitation-compatibility.
kanzure: blah
kanzure: i wasn't claiming i was mass manufacturing anything like that at home
kanzure: asciilifeform: pick and places are getting pretty cheap... though this one might still be out of my budget range: https://www.youtube.com/watch?v=SRu02F6AOmg&t=40s
kanzure: that's only because we're idiots
kanzure: if making anything always requires me to make impossible investments in time and energy then none of the fun stuff will get made
kanzure: that's not what i mean
kanzure: microelectronics vlsi doesn't require millions (well.. i mean.. not to make a single chip)
kanzure: basically i want hardware but i don't want to have to spend my life reading millions of pages of documentation
kanzure: hmm then i will pencil that in sometime
kanzure: have i ever ranted to you about my apt-get for hardware stuff
kanzure: basically ghetto projector pointed down microscope tube
kanzure: planning on same system for microfluidics adventures
kanzure: asciilifeform: i have various parts laying around for homefab of microelectronics (on the order of a few hundred microns but whatever)
kanzure: asciilifeform: here are some things i was looking at yesterday http://diyhpl.us/~bryan/papers2/mems/
kanzure: i am also fond of things on the order of "resistive heating element + some surface" heh
kanzure: mhd looks like it could work
kanzure: asciilifeform: i actually am very fond of linear screw actuators, but i would prefer something that can be manufactured using spatial light modulation with basically zero assembly steps.
kanzure: or car... but it wont really ever be used in a car i hope..
kanzure: let's say powering a conventional cnc machine maybe
kanzure: why can't i just have lots of reusable motion devices? >:(
kanzure: anyway this is not for micromotion
kanzure: how about alibaba
kanzure: gah why did you send to me ebay
kanzure: ebay is selling surface mount lasers that do >1 kW? hrm /me looks again
kanzure: yeah but nobody is selling me a multi-kilowatt surface mount laser
kanzure: also for cell lysis but w/e
kanzure: someone made a laser-pumped microfluidic device which was cute
kanzure: fascinating
kanzure: of bottles?
kanzure: having a flat/planar/single-pass-manufactured engine or actuator would be very useful for many reasons
kanzure: vaguely connected i suppose
kanzure: right... nobody in their right mind should use youtube.. yet here i am.
kanzure: a minute on youtube saves a decade in my lab
kanzure: perhaps https://www.youtube.com/watch?v=h_DjbYZ2eCM
kanzure: hm no
kanzure: https://www.youtube.com/watch?v=13JW-Ifg4wA
kanzure: where should i look for evidence of large force magnetohydrodynamic actuators
kanzure: hm i have a magnetohydrodynamics person in hplusroadmap. i will pester him.
kanzure: or at "large" scale
kanzure: except it doesn't work for large amounts of force
kanzure: a comb drive is approximately what i want
kanzure: since asciilifeform seems to understand i'll drop it
kanzure: i'm not sure if mircea_popescu is being serious about this
kanzure: oh that doesn't matter, you can convert most forms of motion
kanzure: linear screw thread actuators are very useful at all sorts of sizes, but hard to manufacture (= require more steps and parts and manufacturing processes)
kanzure: nothing in particular, just generic actuators i guess
kanzure: that's more the reason here
kanzure: but more would be nice
kanzure: asciilifeform: at minimum i need a few tens of newtons of force... in general.
kanzure: (i dropped out)
kanzure: well that's what you get when mechanical engineering departments spend more time teaching me fucking excel spreadsheets than, you know, engineering
kanzure: i would say "printable engine" except then i would hate myself
kanzure: correct
kanzure: it means "don't spend 100 hours assembling tiny parts into a bigger device"
kanzure: hm
kanzure: asciilifeform: yes please. although other one-pass manufacturing processes will be considered.
kanzure: hm.
kanzure: wikipedia image does not make me think a tesla turbine is flat
kanzure: asciilifeform: i'm thinking of something like http://en.wikipedia.org/wiki/Scroll_compressor