log☇︎
163700+ entries in 0.094s
a111: Logged on 2017-08-28 20:16 kanzure: basically i sat down and tried to figure out what is the most controversial idea i could possibly construct
mircea_popescu: oh, that's what you meant.
kanzure: it's hell of a way to spend one's life, that's all.
a111: Logged on 2017-08-28 20:12 kanzure: alright well that's lame.
asciilifeform: evidently that ain't enough, or, e.g., software would work
kanzure: asciilifeform: turns out you have to actually pay people to do things
kanzure: asciilifeform: i have someone else working on a very similar project these days. it's in progress.
mircea_popescu: really, "i wonder what happened to the clouds, i've not been out of basement for a decade, poor clouds, they must be faring poorly"
asciilifeform: kanzure: mike w promised myostatin inhibitor to me in 2007 !!1111 where is it ?! ☟︎
a111: Logged on 2017-08-28 16:16 asciilifeform: shinohai: 'What's the latest on Mircea? I've not heard about him in a while.' 'I think his followers actually kind of excommunicated him after he lost their bitcoins. I don't pay much attention to them though.' << didjaknow !
mircea_popescu: http://btcbase.org/log/2017-08-28#1703817 << ahaha what is this dumb shit ? ☝︎
mircea_popescu: kanzure i read the logs anyway.
mircea_popescu: THIS is what your money's fucking buying omfg, "i live in the country so i can spend 80k a year on renting a cardboard box and have nice coasters which are worse than a fucking pile of dried goat shit"
kanzure: about to get unvoiced i think. could someone offer mircea_popescu a link to the right place in the logs for the eugenics war.
mircea_popescu: AND the dumbass cardboard gets destroyed by water.
mircea_popescu: now : the sheen on the top adheres to wet glasses, which in this climate is ALL of them. so you get floating coasters.
asciilifeform actually has some gold coasters. ( they're dud mitsui cd-r, gold, yes ! )
mircea_popescu: cuz i TOTALLY need pretty colorful pictures on my fucking coasters, lest my brain turns off or some shit.
mircea_popescu: here's the problems with "expensive, upscale" coasters : they're not a square of cut up cork, like you'd expect if they were you know, uncivilised, unglamorous, un-internet-of-things orcfare. no. they're a thin strip of cork glued to cardboard with some shiny drawings on top. ☟︎
mircea_popescu: and in other shit i will now randombly whine about : i bought these coasters, right ? cuz i was in some random mall picking up some chick and we went in an "upscale" libreria and well, i dunno, i impulse bought some fucking coasters. she thought they were expensive.
mircea_popescu: i guess. there's an inch of soil and under that basalt, you understand. there's a reason jungle soil is poor -- all of it gets washed into ocean.
asciilifeform: mircea_popescu: large peltier with drain hose ~cured my 'too hot, too wet'
mircea_popescu: shinohai if i lived in a jivilized country with jews in it i'd just have some cabbage juice. sadly, no cellars here. too hot, too wet.
mircea_popescu: the problem with hanging out with sluts is well known to soccer moms. kids are fine, you're fucking dead.
kanzure: first you have to kill everyone who has ever had a headache...
kanzure: i don't know any hereditary magic tricks to eliminate headaches but that should be doable.
deedbot: http://trilema.com/2017/the-day-of-failure-trilemma/ << Trilema - The Day of Failure Trilemma
kanzure: well i was thinking about just going for the heart of the whole thing (designer genomes/eugenics) and go after those bathtubs
asciilifeform: at any rate, if kanzure knows how to make, e.g., transgenic muscle men, or thicker bone, etc. he should not settle for small change, go, make
kanzure: i read all logs everywhere. it's sort of my thing.
asciilifeform: ( this is in the l0gz somewhere, ancient thread , if you give a damn )
asciilifeform: kanzure: objective was to economically make (by the kg) a (modified) butyrylcholinesterase ☟︎
asciilifeform: kanzure: i and ~50 other folx, lost jobs, because it proved ~impossible to persistently force $valuableprotein secretion in ecoli ☟︎
BingoBoingo suggests sticking to the basics. P53 overexpression, Myostatin inhibition, and let the dice go on everything else ☟︎
asciilifeform: very, very easy, to make $tech work on... paper.
kanzure: well there's some ecoli results for you.
asciilifeform: i suspect -- difficult to reduce to practice.
asciilifeform: this was worked as ancient sf plot : breed 'nonvirusable' folx, then plaguenuke everybody else
kanzure: also, i am part of hgp-write (basically human genome project 2.0) one of our projects is removing 7 codons from the genome to render human biology impervious to all existing viruses. ☟︎
asciilifeform: but where is the causative link ?
asciilifeform: people over 2 metres tall, same
kanzure: wwc1 t/t carriers tend have >19% improvement in working memory performance
asciilifeform: which suggests that ~whole field consisted of 1 part 1980s tech ( largely working on ecoli ) to 99 parts hypolade.
asciilifeform: so far the volume of ~interesting~ result with meaningful pvalue, is -- afaik -- 0
kanzure: optogenetics is one way of interactive toggle (usuaully using neuronal receptors but there are other techniques such as light-sensitive cas9/recombinases/etc)
kanzure: anyway, you don't need to focus merely on small mutations, you can also voluntarily delete chunks of chromosomes or whatever ☟︎
kanzure: yes well online interactive toggling is also a possible thing
asciilifeform: and that we know jack shit re the effects of the loci UNTIL SOMEBODY TOGGLES'EM AT WILL ☟︎
BingoBoingo: lol, this is their take on a common mutation: "The polymorphisms rs1800497 and rs2283265 (also known as the Taq1a polymorphism) near the dopamine receptor 2 (DRD2) gene are associated with improvements during working memory training. (rs1800497(C;C) better avoidance of errors). However this polymorphism comes with serious tradeoffs: antisocial, borderline, dissocial, and avoidant personality disorders, addictive and impulsive behaviors s
asciilifeform: concern is that literally the entire document linked earlier, is ~content-free
asciilifeform: but somehow same thing does not appear ridiculous to literate folx, when done in meat ??
asciilifeform: picture if some martian got a hold of a number of pc and gave them same treatment as the geneticists : 'mov rar, [ecx + ebx] at 0x40000000 associated with 0.5% increased memory allocator performance !!1111'
kanzure: and also the effect size is minimal in many cases.
kanzure: well in many cases the mutations listed on that page have not been documented (on that page) as impacting positively or negatively. so the document should not be considered a definitive lookup table. ☟︎
asciilifeform: re the linked piece, i'm not satisfied with the direction of the causal arrow having been established ☟︎
kanzure: so i guess to answer your question, ethnic cleansings?
kanzure: here's some background on plausible modifications that are aleady well known http://diyhpl.us/wiki/genetic-modifications/
kanzure: i am proposing an aggressive timeline like 100 designer baby genomes by 2030 and then 1 million designer babies by 2045
kanzure: basically i sat down and tried to figure out what is the most controversial idea i could possibly construct ☟︎
BingoBoingo: kanzure: What's the worst that happens if you pitch in a public log?
asciilifeform: i can't speak for him, but i only very vaguely know you, kanzure , through n-th degree meatspace .
kanzure: should i be hurt that he doesn't know me?
asciilifeform: i'll also warn that neither mp nor most of the folks here, engage in 'private' conversation with folx they do not know.
kanzure: yeah maybe not appropriate for public logs at the moment
kanzure: i have begun to master the art of sleeptyping so sleep is no longer an inconvenience
asciilifeform: or you can speak now and he'll read the logz and maybe answer.
kanzure: alright well that's lame. ☟︎
kanzure: where precisely do i go to pitch mircea on eugenics 2.0?
BingoBoingo: Now that's Qntra worthy
asciilifeform: in other lulz, https://archive.is/n1IbD >> 'The training of today’s SWOs was further eroded by the Pentagon’s focus on the wars in Iraq and Afghanistan. Before 2010, many Navy officers who were expected to learn on the job were not on ships at all. During critical times in their professional development, they were taken away from their ships and sent to serve as individual augmentees with soldiers and Marines fighting in land-bas
jhvh1: asciilifeform: The operation succeeded.
asciilifeform: !~later tell ben_vulpes http://wotpaste.cascadianhacker.com/pastes/Gy3K7/?raw=true
asciilifeform: i dun see any thinking in there
shinohai: Some people shouldn't be allowed to think.
asciilifeform: shinohai: 'What's the latest on Mircea? I've not heard about him in a while.' 'I think his followers actually kind of excommunicated him after he lost their bitcoins. I don't pay much attention to them though.' << didjaknow ! ☟︎
a111: Logged on 2017-08-28 02:25 BingoBoingo: <mircea_popescu> which one was stormfront again ? << The forum for which the Weev Daily Stormer was named, but no relation
asciilifeform: http://btcbase.org/log/2017-08-28#1703794 << i thought it was named for the obvious, der sturmer ☝︎
mircea_popescu: oglaf author ? totally.
ben_vulpes: "this woman is a treasure"
deedbot: http://phuctor.nosuchlabs.com/gpgkey/C376A7AC72465727A5D5ECC12B096A812963EAEDD5896FD486D55178BA749249 << Recent Phuctorings. - Phuctored: 1592...9353 divides RSA Moduli belonging to '207.162.8.196 (ssh-rsa key from 207.162.8.196 (13-14 June 2016 extraction) for Phuctor import. Ask asciilifeform or framedragger on Freenode, or email fd at mkj dot lt) <ssh...lt>; ' (Unknown CA QC)
deedbot: http://phuctor.nosuchlabs.com/gpgkey/C376A7AC72465727A5D5ECC12B096A812963EAEDD5896FD486D55178BA749249 << Recent Phuctorings. - Phuctored: 1367...8667 divides RSA Moduli belonging to '207.162.8.196 (ssh-rsa key from 207.162.8.196 (13-14 June 2016 extraction) for Phuctor import. Ask asciilifeform or framedragger on Freenode, or email fd at mkj dot lt) <ssh...lt>; ' (Unknown CA QC)
deedbot: http://phuctor.nosuchlabs.com/gpgkey/F56C06F50CA642FFEBE26155AE8715AA520DB5DA7D3F85021F43866AA14E1F69 << Recent Phuctorings. - Phuctored: 1220...4639 divides RSA Moduli belonging to '91.109.28.51 (ssh-rsa key from 91.109.28.51 (13-14 June 2016 extraction) for Phuctor import. Ask asciilifeform or framedragger on Freenode, or email fd at mkj dot lt) <ssh...lt>; ' (s445.deinprovider.de. DE)
deedbot: http://phuctor.nosuchlabs.com/gpgkey/F56C06F50CA642FFEBE26155AE8715AA520DB5DA7D3F85021F43866AA14E1F69 << Recent Phuctorings. - Phuctored: 1021...0923 divides RSA Moduli belonging to '91.109.28.51 (ssh-rsa key from 91.109.28.51 (13-14 June 2016 extraction) for Phuctor import. Ask asciilifeform or framedragger on Freenode, or email fd at mkj dot lt) <ssh...lt>; ' (s445.deinprovider.de. DE)
mircea_popescu looks through the list of forgotten boxen
danielpbarron: i don't wanna spoil the surprise just yet. let's see if she shows up
BingoBoingo: danielpbarron: Wait, more kicking off of things?
BingoBoingo: <mircea_popescu> which one was stormfront again ? << The forum for which the Weev Daily Stormer was named, but no relation ☟︎
mircea_popescu: danielpbarron such lulz. "oh, it's totally not a honeypot". really ?
mircea_popescu: anyway, they should write to google. iirc they are now hosting kerbs on their "totally not for bloggers" shared server, what's another one.
danielpbarron: apparently tor is only for hiding pedophiles
mircea_popescu: lol wait what, "kicked off tor" ? isn't that what tor's for ?
danielpbarron: white nationalist website kicked off tor, should be someone incoming to channel re: this
BingoBoingo: Anyways, apparently the Orchard has pushed Stormfront offline now.
mircea_popescu: BingoBoingo aha. seems rather exactly the pantsuit next play.
BingoBoingo: "Big Ron had Sensei Steve and I out to watch the big fight, in which we all cheered for the white man in the ring—Floyd Mayweather." >> http://www.jameslafond.com/article.php?id=8775
mircea_popescu: who can afford to pound a pound of almond seeds into fine dust by hand ? teh sultan of swing, and him only!
mircea_popescu: and in today's ancient trilemas : http://trilema.com/2012/martipan/
mircea_popescu: teh very respectable southern poverty law center. and i bet you bitcoin to donuts they didn't actually pay jack for it, either. ☟︎☟︎☟︎
mircea_popescu: since ben_vulpes linked http://trilema.com/2014/guidance-there-is-no-such-thing-as-bitcoin-taint/#footnote_3_52853 i suppose it's time to edit that footnote to link to http://trilema.com/2014/interacting-with-fiat-institutions-a-guide/ ?
mircea_popescu: but in any case prolly safe to say that the problems of the westerners were solitude, and inferiorty complex v-a-v majesty of nature. couldn't give less of a shit re "problems of society" for lack of one, or any desire for one. certainly the women had the healthy "if there's a cock i'm sticking in into me" attitude.