log☇︎
681700+ entries in 0.458s
asciilifeform: some of us live for the unicorn hunt.
mircea_popescu: <asciilifeform> good sovereign << a cryptozoological animal << this reduces to saying there's nothing to live for.
Apocalyptic: mircea_popescu, are you ordered too ?
mircea_popescu: check it out, google has managed to erase history. the only winner of nurenberg doesn't exist in the brave new world.
gribble: Use immense in a sentence | immense sentence examples: <http://sentence.yourdictionary.com/immense>; It gives me immense pleasure to inform all the members and ...: <http://www.b-u.ac.in/bu-icai/syllabus.pdf>; Immense | Define Immense at Dictionary.com: <http://dictionary.reference.com/browse/immense>
mircea_popescu: ;;google "is a source of immense satisfaction to me"
nubbins`: unfortunately, picking a good sovereign likely requires you to pass through the hands of the worst sovereign of them all (int'l border control)
asciilifeform: 'you commit atrocities with the sovereign you have, not the sovereign you wish you had.' (apologies to mr bush)
nubbins`: or rather, where the enforcing of said ordering is a common occurrence
mircea_popescu: the only solution is to pick a good sovereign and stick to it.
mircea_popescu: nubbins` naive copout that. you're always ordered.
mircea_popescu: just like turing.
mircea_popescu: BingoBoingo that's right.
nubbins`: more for following the wrong ones
mircea_popescu: one day people will hang for just following orders in what once was washington, dc, too.
BingoBoingo: http://crazy-meds1.blogspot.com << this guy << His pre-CNS collapse occupation if you read deep enough, Big Iron Programmer.
TheNewDeal: gribble quit it with the ">;" crap
gribble: The Last Psychiatrist: <http://thelastpsychiatrist.com/>; The Last Psychiatrist Archives: <http://thelastpsychiatrist.com/archives.html>; The Last Psychiatrist: Who Bullies The Bullies?: <http://thelastpsychiatrist.com/2014/05/cyberbll.html>
asciilifeform: ;;google the last psychiatrist
asciilifeform: by and large, they 'are only following orders' - as described by, e.g. TLP. but still.
mircea_popescu: medical profession maybe not, but the "mental health" "professionals" definitely.
asciilifeform: (likely that, in the future, folks will view today's medical profession in much the same light we see herr mengele)
TheNewDeal: I like this guy alreadh
asciilifeform: if before dr. mengele got to him - there was - certainly not after.
mircea_popescu: asciilifeform i know dude. the idea is there's no such thing in there
mircea_popescu: http://crazy-meds1.blogspot.com << this guy
TheNewDeal: who has this list?
mircea_popescu: Past meds (likely incomplete): Abilify, clonazepam, desipramine, diazepam, Gabitril, lithium, Neurontin, Paxil, prochlorperazine, Provigil, Prozac, Risperdal, Seroquel, Serzone, Strattera, Trileptal, Zyprexa"
mircea_popescu: "Current meds: lamotrigine 300mg, topiramate 325mg, buspirone 60mg, protriptyline 60mg, EPA 600mg, methylphenidate 5-10mg, lorazepam 1mg PRN
asciilifeform: in this scenario, the 'cerebral' work was done for you - by the folks who built the plant which churns out pseudoephedrine by the gigaton
TheNewDeal: or you just have to know people that steal a gigaton of the precursor?
asciilifeform: it is again - when the one-step precursors are unavailable
mircea_popescu: now they have a reality show abvout it
mircea_popescu: people thought organic synthesis is a cerebral endeavour
mircea_popescu: before every hick set his garage on fire trying to make meth
asciilifeform was involved in a (failed) project to churn out butyrylcholinesterase via transgenics.
mircea_popescu: people microbrew, god love them.
asciilifeform: a world where coke is the currency and sugar is illegal... an agro product << point of the second (e. coli) gedankenexperiment isn't that the planet needs a gigaton of coke (perhaps it does, but i digress) but would be to profit maximally off the 'demonetization.'
mircea_popescu: asciilifeform you say this on the basis of what.
asciilifeform: coke market in the us would be like meth market << nope. bioreactor (aside from somebody having to jump the hurdle and produce the transgenic critter in the first place) is a considerably more cerebral undertaking than grignard reaction in a garage.
mircea_popescu: actually coke is very similar to fructose
TheNewDeal: I was going to say, Coke is verrry similar to sugar
TheNewDeal: wait are we talking about Coke or coke
asciilifeform: genetically diddling e-coli is tricky.
mircea_popescu: if this were true coke market in the us would be like meth market
asciilifeform: (bacterium is energetically-cheaper than plowing fields)
asciilifeform: could easily become the same kind of 'agro product' as... insulin.
mircea_popescu: so your gedanken experiment could well be carried out in a world where coke is the currency and sugar is illegal.
mircea_popescu: coke is an agro product. and for that matter, quite similar to sugar
asciilifeform: (coke is no more difficult to churn out by the gigaton than, e.g. progesterone. do you see it at local pharmacist for a penny a dose? didn't think so. because it is a kind of chemical / international fiat currency. with all of the features that come with such.)
mircea_popescu: Mats_cd03 welcome to -assets, where you broaden
mircea_popescu: apparently it's a thing
mircea_popescu: fun fact : psychiatrists with child practices occasionally get to see cases of prepubescent kids that anally masturbate with their shit and end up with serious constipation issues
asciilifeform: cocaine demonetization is, of course, gedankenexperiment. nobody interesting is particularly well-positioned to benefit from it, and so it won't happen - just as cardboard full-height replica of eiffel's tower won't happen.
mircea_popescu: asciilifeform well now that all depends.
moiety: they have started bowel screening here for the 50+. you get cardboard sticks and instructions to shit on your bagged hand and smear it on a chart with said sticks, which you do over the course of X days and send it off to the GP
asciilifeform: columbia << not a military giant who can make the 'demonetization' stick globally.
Mats_cd03: dafuq am i going to do with freezer bags
BingoBoingo: The only significant problem with MAOIs was they prevented selling the patient other drugs... at least drugs that aren't amphetamines
moiety: i had a patient that was on so many conflicting medications his liver was shutting down. every time i saw him, he was thinner and felt worse and they just wouldn't do anything. i'm worried what happened to him since i left
asciilifeform notes similarity to the software 'industry'
BingoBoingo: It's usually how things work
mircea_popescu: moiety those were babies
asciilifeform: i've met folks taking 5+ psych meds, mostly against... each other
asciilifeform: the basic formula of antidepressant market: 1) http://log.bitcoin-assets.com/?date=18-06-2014#722631 2) side effects are a gift from the gods: 10 side effects - 10 kinds of pill you can now sell. ☝︎
BingoBoingo: impotence, inability to orgasm,... the full set is rather large
BingoBoingo: moiety: Here Bupropion is used frequently when people discover aspects of the SSRI side effect profile.
BingoBoingo: Seems drugs can have problems too
gribble: Old Nardil Vs. New Nardil - Emsam and other MAOIs - Crazy Talk ...: <http://www.crazymeds.us/CrazyTalk/index.php/topic/5897-old-nardil-vs-new-nardil/>; Nardil and Dry Mouth - Depression: <http://depression.emedtv.com/nardil/nardil-and-dry-mouth.html>; Drug Ratings for NARDIL - Ask a Patient: (1 more message)
BingoBoingo: asciilifeform: Of course, well at least it has been since MOAIs fell to the wayside.
asciilifeform: BingoBoingo: the basic idea behind the 'antidepressant' market is at least as mistaken as the phlogiston theory. so what kind of result can be expected.
asciilifeform: learn how alchemists were treated back when influential folks thought that alchemy might work
moiety: bupropion is given rarely here as an antidepressant but more as an anti smoking thing, as its not licensed in the same was as in the us
asciilifeform: btc folks who expect to 'can have problems' from daring to demonetize the dollar should contemplate gedankenexperiment - what'd happen to a nation that 'demonetizes'... cocaine. (that is, establishes dirt-cheap production & distribution.) if your starfish doesn't quiver at the thought of the 'problems you can have' then...
moiety: i get the kitten post now. good work mircea_popescu lol you need to source some ar ones.
asciilifeform: which is the way usg likes it.
BingoBoingo: (The interesting part is the picture... check the ring)
asciilifeform: BingoBoingo: so weak as to be almost useless.
assbot: Bupropion - Wikipedia, the free encyclopedia
BingoBoingo: asciilifeform: They founf a dopamine and norepinephrine reuptake inhibitor in Bupropion. Note the substitution that was made... https://en.wikipedia.org/wiki/Bupropion
moiety: is it just me or does the trilema header change more frequently these days?
asciilifeform: this is why the 'optimize for patentability' process is an inevitable crock of shit. when the scamz0rs can't enclose the commons - they torch them.
asciilifeform: interestingly, sometimes the pharma folks fail: they spent some years trying to cough up a dopamine reuptake inhibitor that doesn't reduce to a synthetic cocaine, and, afaik, gave up ☟︎☟︎
asciilifeform: in both examples, ordinary opium is the champ
asciilifeform: talking about the goal, vs. the process
Mats_cd03: brute force all of the things. see what works, rinse, repeat.
asciilifeform: Mats_cd03: 'let's take a drug that's been known for 5,000 years, but is too much fun; nip at the structure a bit until we have a - anti-diarrheal, cough suppressant, etc. that's almost as good as opium.'
Mats_cd03: i may have used it a few times to punish a thief in the office
asciilifeform: Mats_cd03: interesting case of the kind of thinking that gave us, e.g. DXM
assbot: Loperamide - Wikipedia, the free encyclopedia
Mats_cd03: for future reference, the no poo pills i was referring to http://en.wikipedia.org/wiki/Loperamide
moiety_: googles not translating well for me D;
moiety_: are they yours?
moiety_: mircea_popescu: they are so tiny! so cute, but they need some biscuits
assbot: Pisicute pe Trilema - Un blog de Mircea Popescu.
TheNewDeal: what if he is accomplishing both at the same time
Mats_cd03: i can't tell if you're trying to bait college feminists into marketing trilema
gribble: Bitstamp BTCUSD ticker | Best bid: 603.31, Best ask: 606.71, Bid-ask spread: 3.40000, Last trade: 604.58, 24 hour volume: 6255.76911036, 24 hour low: 580.0, 24 hour high: 608.88, 24 hour vwap: 595.9930859
TheNewDeal: like Nikola Tesla nuts or Timothy McVeigh nuts?
mircea_popescu: they'd have like beer parties dedicated to discussing just how fucking just not done such deeds are.