652400+ entries in 0.444s

mircea_popescu: i mean,
the
trope itself, "eschatological contagion" is like what, 1/3 of all of it ?
mircea_popescu: newton got hit in
the head by a falling apple... "hmm how could i
turn
this bump into a research grant"
chetty: well
these days most science seems
to get
the answer it wants first,
then work backwards
to
the question
mircea_popescu: that's
the halmark of speculative fiction. it asks science "and why not" an' science dunno.
BingoBoingo: Lack of historical Small Pox exposure made Americans vulnerable
to distilled spirits?
mircea_popescu: in fact, it COULD be
that aids-as part of genome is what makes niggers niggers. as unpleasant at
that sounds, it's at least possible, scientifically. yet none of
the speculative fiction folk with an axe
to grind are using it.
BingoBoingo: Imagine if Khan swung
through Africa before hitting Europe and introduced diseases other
than "classic" plague
mircea_popescu: for all you know it was part of
the ancient egyptian genome, now extinct.
mircea_popescu: think of it : monkeys don't suffer much from it, so it's been around for a while. sure yurpeans "discovered it" but it can't possibly be
the first case of interaction.
BingoBoingo: Well,
the it is definitely in particular person's genomes now, but... not across most of
the species
BingoBoingo: At least it isn't in
the human genome like Herpes
BingoBoingo: AIDs
though is weird because of how
the virus adapts
to drugs in situ. Maybe part of
this is just drugs
that fight it do so by fucking with DNA/RNA expression... Maybe it is just
that much of a natural asshole.
mircea_popescu: who's in charge of
the lab
that raises
the
tobacco growing it ?
mircea_popescu: who
the fuck led
the research effort
that made ebola strain '#2 ?
mircea_popescu: yet i have no idea who even came up with
those
things.
mircea_popescu: i
think
the biggest problem bar none of modern society is
that average derp can name a dozen "puas" or "important feminists" or whatever
th fuck
BingoBoingo: <mircea_popescu> and like last year something
that works as a pre-emptor. <<
Truvada is
the
trade name, but
this pre-exposure prophylaxis
thing has been common for exposed medical workers for years.
The new
thing is someone let
the secret out of
the bag.
BingoBoingo: Yeah. AIDs and
the resistance it develops is weird.
mircea_popescu: and like last year something
that works as a pre-emptor.
mircea_popescu: basically making it a case of "fu for having
taken our medicine".
mircea_popescu: however,
the people
that had
taken pill 1,
then a cockail of 1+2 would be significantly less effecual.
mircea_popescu: if one had never
taken pill 1,
then a cocktail of 1+2 would stop
the virus for
them, pretty much resolving
the problem. it'd never clear, but it'd never advance.
ben_vulpes: (<Pilate> .hiv pre-registration up
this morning... apparently i reserved spread.hiv, spreads.hiv, super.hiv, and selling.hiv)
mircea_popescu: only years later a 2nd
thing was found.
the magic involved was pretty evil, however :
ben_vulpes: (topical: .hiv pre-registration went up
today)
BingoBoingo: mircea_popescu> BingoBoingo afaik
there was. << Problem is living cells (where antibodies don't go) harbor
the pathogen in
the case of AIDs
mircea_popescu: so, aids "had no cure" for a while in
the disco era. but
then, late 80s/early 90s a certain
thing was found
that'd slow down its rate, adding 5 maybe 10 years le if well managed. after much hand wringing
this was released
to
the public,
mircea_popescu: actually, im glad i got you pinned here bb, cause i wanna run
this by you see what you
think.
BingoBoingo: Also why
there's no Aids serum working on
this principle
chetty: dont dispair,
there are always prions
BingoBoingo: Well,
this stuff
takes
time, but yeah... One
thing
that makes
this easier on Ebola and harder on say
the flu
though is... Ebola doesn't stay latent in cells
mircea_popescu: it's vanishingly improbable for an antibody
to not exist.
thus finding it becomes a matter of... well... how much hashing you're doing
mircea_popescu: tbh i
think
this
throws a monkey wrench in
the future viability of "big pandemic" scenarios.
ben_vulpes: guess
the biologists are useful after all
BingoBoingo: mircea_popescu:
The antibodies bind
to
the virus and... Boom
mircea_popescu: this is sick, so basically
they're inserting
the missing antibodies
thus allowing macrophages and whatnot
to clear it ?
BingoBoingo: Generally
though if you get a monoclonal antibody
that
targets something, it's going
to kill it.
The remarkable
thing is
they went ahead and found
three just
to be safe.
chetty: mircea_popescu, apparently not,
this serum appears
to be curing it
BingoBoingo: The serum's basically 3 different antibodies for
three different
targets on
the Ebola virus found by giving mice ebola until
they could create clonal lines for
the cells producing
these antibodies and
then making
tobacco grow it all
chetty: BingoBoingo, yeah it actually sounds pretty yucky, but I suppose if you are about
to die of ebola ...
BingoBoingo: chetty> lmao,
that magic serum
they are
testing for ebola, made from
tobacco << Mouse antibodies made inside a
tobacco plant!
mircea_popescu crafitly stops himself before saying something dumb like "about
the same
texture,
too" and inadvertently giving
the whole charade away
chetty: I like
the big ones better
mircea_popescu: i am having
the cutest avocado in
the whole world. roughly
the size of an ovary.
chetty: lmao,
that magic serum
they are
testing for ebola, made from
tobacco
mike_c: spoiler alert:
trilema
transitioning
to contraquadlema
assbot: The pseudo-Bitcoinsphere feels just as squishy-poo as
the Romanian pseudo-blogosphere felt five years or so ago. pe
Trilema - Un blog de Mircea Popescu.
mircea_popescu: well aaactually
that's part of what i was going
to announce.
mike_c: mircea_popescu, when does
trilema join
the future?
BingoBoingo: mike_c> and now van-ads degenerates into us out-bidding each other
to
troll each other's blogs :) <<
This is how markets begin.
mircea_popescu: and actually speaking of it : making a collision for 4 byte short ids is not
that hard. i hope you check against fingerprints ?
mircea_popescu: and add a fucking cr , im sick of fishing
the otp out from 33ae4284-cdba-46a1-b0ae-8f94f23b74acmirce
mircea_popescu: because of ben_vulpes
there's going
to be a lot of extra ;;ident spam in here because fuck me if im going
to
type my keyid.
assbot: WarOfLife (S.WOL), July 2014 Statement pe
Trilema - Un blog de Mircea Popescu.
BingoBoingo: What, I
tied of seeing
the default van ads while compulsively reloading MPIF
tracker
mircea_popescu: actually i was going
to make some announcements but IVE BEEN
TOO BUSY SLEEPING AND WITH PERSONAL MATTERS
mike_c: and now van-ads degenerates into us out-bidding each other
to
troll each other's blogs :)
ben_vulpes: compliments on
technical excellence should be delivered
to yours
truly
ben_vulpes: blame mircea_popescu
the rules are his fault
mike_c: ad network of
the future
pankkake: if you provide me with a CSS (or even a full
template, venus,
the
thing used
to generate
the planet, has
templates), I'll enable it
ben_vulpes: survant james'd be happy
to do it for 1 BTC
ben_vulpes: can we get log.bitcoin-assets.com styled for mobile
too?
pankkake: (and it used
to be only goatse)
pankkake: by
the way, images are replaced by goatse for ip*ds
pankkake: for
the lulz,
though I've had enough lulz after a few years
mircea_popescu: i mean, so
they're hipsters. we don't
take
them
to bed. you won't even sell
them liquour now ?
punkman: mircea_popescu: numbers what do
they even mean
pankkake: sometimes I
think of banning all macs and all chromes, or removing
the
thing
pankkake: it's on
the whole server, iP*ds are banned
mircea_popescu: mp "what's wrong with using blogs.b-a for a news source ?" op "Whats wrong with it is
that if you visit with an iOS device, youre redirected
to a page
that says no hipsters allowed."
assbot: The pseudo-Bitcoinsphere feels just as squishy-poo as
the Romanian pseudo-blogosphere felt five years or so ago. pe
Trilema - Un blog de Mircea Popescu.
punkman: "The program has brought in more
than $150 million in restitution and fines via five cases from eight whistleblowers.
That has
translated
to more
than $15 million in payments
to
the whistleblowers, including a $14 million jackpot
to one person. "
assbot: Meet
the SEC's 6,500 Whistleblowers - WSJ
[]bot: Bet placed: 1 BTC for No on "Gold will close above USD 2000 in 2014"
http://bitbet.us/bet/759/ Odds: 28(Y):72(N) by coin, 35(Y):65(N) by weight.
Total bet: 8.928482 BTC. Current weight: 40,835.
fluffypony: so I
think he's convinced enough people
that he holds
the key
to
the future
BingoBoingo: ben_vulpes: Well, you have
to fight
their Pidgin with jargon
fluffypony: BingoBoingo: I'm pretty sure
this isn't like MaidSafe - Vitalik does
the
tour circuit, and he's been building up
to
this for a while